Efficacy of Anti-TNFα in Severe and Refractory Neuro-Behcet Disease
نویسندگان
چکیده
منابع مشابه
Efficacy of Anti-TNFα in Severe and Refractory Neuro-Behcet Disease
To report the safety and efficacy of anti-tumor necrosis factor α (TNFα) therapy in severe and refractory neuro-Behçet disease (NBD) patients.Observational, multicenter study including 17 BD patients (70.6% of male, with a median age of 39.3 [24-60] years), with symptomatic parenchymal NBD, refractory to previous immunosuppressant and treated with anti-TNFα (infliximab 5 mg/kg [n = 13] or adali...
متن کاملMagnetic resonance imaging and Neuro-Behcet Disease.
Behcet disease is a rare multi-system immune related vasculitis which may involve the central nervous system, usually during the course of the illness. Magnetic resonance imaging is currently the modality of choice for the detection of the parenchymal lesions in their different phases, as well as the dural sinus venous thrombosis.
متن کاملRole of diffusion-weighted MRI in Neuro-Behcet`s disease.
We report the findings on serial diffusion-weighted MRI in a 29-year-old male with neuro-Behcet`s disease. Initial T2-weighted and fluid-attenuated inversion recovery images showed a hyperintense lesion in the brain stem. The lesion showed slight hyperintensity on diffusion-weighted images with no evidence of diffusion restriction on apparent diffusion coefficient maps. A follow up study after ...
متن کامل[Behcet disease].
Central nervous system involvement in Behçet disease (BD) may be either parenchymal or nonparenchymal. Abnormal cerebrospinal fluid findings and parenchymal involvement are associated with a poorer prognosis. A self-antigenic role for HLA B51 has been postulated in the pathogenesis of BD. The sibling occurrence rate is 3.6%. Familial aggregation may be more pronounced among pediatric cases comp...
متن کاملImmunology of Behcet disease: review article
Behçet's disease (BD), also known as the Silk Road disease, is a multisystemic and rare inflammatory disorder primarily prevalent in populations along the Mediterranean Sea. Today, BD is defined as a crossroad between autoimmune and auto-inflammatory syndromes. Variety of syndromes including mucocutaneous manifestations such as oral and genital ulcers, papulopustular lesions and erythema nodosu...
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ژورنال
عنوان ژورنال: Medicine
سال: 2016
ISSN: 0025-7974
DOI: 10.1097/md.0000000000003550